Specialists at the New Medical Technologies Center conduct significant scientific research in order to find ways to prevent the infection of patients with viruses, that are currently incurable. The large-scale use of the latest medical devices and methods, which prevent the transmission of hepatitis B and C viruses, as well as HIV through medical instruments, will help significantly reduce the spread of virus infections among the population of Uzbekistan.
We wish to present you the know-how – achievement of our science, which can be considered a breakthrough in the field of medicine to protect people from “accidental” infections with currently incurable viruses.
The Unit for inactivation of viruses on medical instruments
Hepatitis B and C viruses, as well as HIV, are transmitted through reusable medical instruments. There are a number of instruments for which sterilization at high temperatures or in harsh chemicals is not an option. The unit inactivates viruses on medical instruments at room temperature without exposing them to strong acids and high temperatures. The principle of operation is to immerse instruments into a solution of methylene blue, and then to photoactivate it by monochromatic light with a wavelength of 590 nanometers and 660 nanometers. Photoactivated methylene blue in the molecules of RNA and DNA viruses blocks two nucleic acids. As a result, viruses lose their cytopathogenicity (ability to infect cells) and replicative activity (ability to multiply).
Scope: the Unit is designed to inactivate viruses on medical instruments (surgical, dental, gynecological, otolaryngological, ophthalmic and others) in medical institutions of various profiles.
The effectiveness of the Unit has been proven experimentally on the viruses of the vaccine strain of poliomyelitis, the viruses of the Crimean-Congo hemorrhagic fever, influenza, hepatitis B and C, as well as HIV infection.
The Unit is registered at the Committee on New Medical Devices and Medicines (General Directorate for Quality Control of Medicines and Medical Equipment) and at the Uzbek Agency for Standardization, Metrology and Certification (Uzstandard Agency).
Method for detecting and assessing the viability of lymphotropic viruses
This is a unique method, which is intended to:
- Increase reliability of determining the infection of biological environments with viruses of hepatitis B (HBV), hepatitis C (HCV) or human immunodeficiency virus (HIV) which are lymphotropic;
- Exclude false negative results when testing donated blood and patients for infection with HBV, HCV or HIV,
- Detect HBV, HCV or HIV in biological material (donated blood, plasma and other blood derivatives) when concentration of viral particles below the sensitivity threshold of the ELISA and PCR method.
- Assess the viability of viruses after exposure to chemical and physical antiviral factors developed and proposed by manufacturers to inactivate viruses in medical practice.
The method for detecting and assessing the viability of lymphotropic viruses is recommended for use in:
- Diagnostic laboratories at various levels;
- Blood donation stations;
- Assessing the antiviral effect of chemical and physical factors.
Utilizing this method excludes errors when testing donor blood and its components for infection with HBV, HCV or HIV viruses. Therefore, the method can significantly reduce the frequency of infection of recipients. Also, this method allows to objectively evaluate the antiviral effect of chemical or physical factors on the viability of lymphotropic viruses.
- Arifbaev Ravshan Salidjanovich – General Director of Centre New Medical Technologies LLC
- Nariman Gulyamovich Gulyamov – MD, professor, developer of the Unit for inactivation of viruses on medical instruments and the author of the Method for detecting and assessing the viability of lymphotropic viruses.